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Tzanck smear Cytology Findings in Pemphigus HHD SSSS Bullous impetigo Dariers disease Molluscum contagiosum Leishmaniasis Candida TEN Hailey Hailey Disease

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Tzanck smear procedure
This video provides a comprehensive overview of Tzanck smear technique in dermatology, focusing on its critical role in diagnosing various skin conditions. It begins with an explanation of how Tzanck smear identifies acantholytic cells, which are keratinocytes with hyperchromatic nuclei, essential for examining erosions or vesicular lesions. The diagnosis of herpes simplex infection is explored, highlighting the significance of multinucleated giant cells as indicators of the virus.

The video also emphasizes the differentiation between pemphigus and Hailey-Hailey disease through direct immunofluorescence, showcasing distinct patterns observable under the microscope. Discussions further extend to the differential diagnoses for discotic acanthotic cells, considering bacterial infections like bullous impetigo, as well as genetic disorders such as Darier's disease. Additional skin disorders such as Staph Scalded Skin Syndrome (SSSS) are discussed, alongside their specific clinical presentations.

Furthermore, the video examines other dermatological conditions, including molluscum contagiosum with characteristic eosinophilic inclusion bodies, alongside candidiasis and the identification of Donovan bodies. Lastly, key features of toxic epidermal necrolysis, including bullous lesions and critical diagnostic indicators, are reviewed. This educational resource is essential for medical professionals aiming to deepen their understanding of cytodiagnostic techniques in dermatology.

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